Inspection Technology


Inspection is a key quality safeguard for pharmaceuticals, and contributes significantly to patient safety. It also helps to improve the entire production process.

Pharmaceutical manufacturers must pay attention to sterile filling and material integrity to ensure the highest product safety. The containers run through many different stages, i.e. washing, siliconizing, sterilizing, filling and closing. They are exposed to different temperatures, pressures, and high-speed movements. This is where inspection technology comes into play.



One single technology is not sufficient to inspect all drugs at the highest standards. Key is to find the most suitable technology for your container type and product.

  • Visual inspection expertise

    Innovative and highly accurate inspection: Camera-based inspection

    Our high-resolution camera systems are robust devices for detection of cosmetic defects and particles in low- to high-viscosity products.

    Reliable and easy to validate: Static division (SD) technology

    A light transmission-based method for moving particle inspection in liquid products.

  • Difficult to inspect products

    Challenging product characteristics

    Some products limit the ability to detect particles. They require advanced know-how and technology.

  • Artificial Intelligence applied to visual inspection

    How can Artificial Neural Network algorithms optimize your inspection results?


    • Detection rates up to 100 %
    • False reject rates down to 0 %


    • System ready for qualification
    • Already in use in manufacturing line


    • Seamless integration into vision system
    • Only 3 vision tools per recipe


    • Potentially millions of dollar in annual savings
    • Less machine idle time for recipe tuning


  • Container closure integrity testing

    Container leaks might lead to a change in the active pharmaceutical ingredient: drugs can lose their efficacy or lead to unexpected side effects.

    Container defects:

    Graphic Container defects

    Laser-based headspace analysis

    Measurement of absorption by oxygen and/or moisture molecules to detect permanent and temporary leaks.

    • Very gentle, non-destructive measuring method
    • Preferred technology for products filled under vacuum or inert gas

    High voltage leak detection

    This container closure integrity testing is based on electrical conductivity measurements. High voltage is applied across the containers filled with conductive liquids. An elevated electrical current indicates a leak.

    • Reliable leak testing even for filling products with low conductance and minimal contents
    • Holistic measuring system to cover the whole container surface
    Ampoule processing
  • Combined machine platforms

    Profit from our modular machine concept

  • Product portfolio
    • Automated Inspection machine for Vials and Ampoules

      AIM 8000 Series: Automated Inspection Machine for Vials and Ampoules

      Designed to handle the wide range of containers at the maximum speed of 600 containers per minute. It can inspect liquids (including highly viscous products and suspensions) and lyo products, either in vials, ampoules or syringes.

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    • Automated Inspection machine for Syringes

      AIM 8000 Series: Automated Inspection Machine for Syringes

      Designed to handle the complex assembly of syringes through proven technologies. Inspect at the max. speed of 600 containers per minute. As an option, AI technology can be added to distinguish particles from bubbles precisely.

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    • Visual Inspection

      AIM 3000 Series: Automated Inspection Machine with CCI testing

      Automated Inspection Machine for ampoules and vials for particulates, cosmetic defects and leak detection at up to 24,000 containers per hour – on one single machine platform.

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    • Modularity for highest flexibility with the AIM3000 Video Teaser

      AIM 3000 Series: Automated inspection machine with modular design for highest flexibility

      Thanks to its modular design, AIM3000 can be adapted optimally and inspect ampoules or vials, liquids or lyophilized products. For CCI testing, high voltage leak detection and headspace analysis are available.

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    • Video about AIM 2000 Series

      AIM 2000 Series: Automated Inspection Machine for Cartridges and Vials

      Proven and reliable technology based on long-term experiences with dental and insulin cartridges. At the maximum speed of 400 c.p.m, vials can be also inspected on one platform.

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    • KHS videoteaser

      KHS: Laser-based headspace analysis machine for automatic leak detection

      Syntegon and Lighthouse Instruments join their complementary strengths to offer best-in-class headspace leak detection machines!

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    • Fully integrated syringe inspection line without glass-to-glass contact

      Fully integrated syringe inspection line without glass-to-glass contact

      Pursuing a fully integrated approach, the line offers a holistic solution for the de-nesting, inspection and re-nesting of pre-filled syringes.

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Ralf Weihbrecht


We´re looking forward to find the suitable inspection solution for your product. Please contact:

Ralf Weihbrecht
Sales Director Inspection Technology and Secondary Packaging
Phone: +49 7151 14-2489